Recently Identified Mechanism of Chronic Stress-Induced Pain

Chronic Stress Is Associated with Pain Precipitation and Elevation in DeltaFosb Expression

Researchers have identified Delta-FosB, an osteosarcoma viral oncogene, as a useful molecular marker of sustained pain. The expression of Delta-FosB is significantly elevated by stress-induced pain, exposing its role in the adaptability of nerves. This study supports theories that Delta-FosB plays an important role in drug addiction, depression, and stress adaptation. The interaction between stress, depression, and pain is something that is not yet well-understood. But, as we learn more about cannabis-based medicine, many of the age-old questions about pain have become much clearer.

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Benjamin Caplan, MDRecently Identified Mechanism of Chronic Stress-Induced Pain

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