Investigation into the flavonoid derivatives of Atriplex tatarica shows that it provides anti-bacterial and anti-biofilm potential against Pseudomonas aeruginosa.
P. aeruginosa is a bacterium that causes infections most frequently in immunocompromised individuals who have been hospitalized for long periods of time. A biofilm is a protective shield that some types of bacteria create for themselves in attempt to protect against host immune system defenses. An infection that evades an immune system can become quickly dangerous should bacterial or biofilm grow in the lungs, kidney, or urinary tracts. Incorporating the flavonoids found in A. tatarica into medical regimen could provide an option for augmenting current treatment for antibiotic-resistant infections. The growth of biofilms, or collections of microorganisms that can grow on a wide variety of surfaces, makes the treatment of Pseudomonas aeruginosa in hospitalized patients with antibiotics markedly more difficult. Certain flavonoids with proven anti-bacterial and anti-biofilm provide an alternative route for helping to manage deadly antibiotic-resistant infections.
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