PTSD Archives - CED Foundation

The Endocannabinoid System and Post-Traumatic Stress Disorder

May 4, 2020 Cannabinoid 1 Receptor, endocannabinoid system, Genetics, PTSD

Genetic susceptibility to posttraumatic stress disorder: analyses of the oxytocin receptor, retinoic acid receptor-related orphan receptor A and cannabinoid receptor 1 genes

In summary

A recent study has found that the dysregulation of cannabinoid receptor 1 (CB1) does not increase the likelihood of developing post-traumatic stress disorder (PTSD). Researchers analyzed genetics to determine if there was any correlation between single nucleotide polymorphisms within the oxytocin receptor (OXTR) gene, the RAR-related orphan receptor A (RORA) gene, and the cannabinoid receptor 1 (CB1) gene and PTSD. It was found that only a genetic variance concerning OXTR was correlated with an increased likelihood of developing PTSD when exposed to shocking traumatic events. Further research may allow for the development of targeted therapies to better prevent PTSD in those at high risk of developing the disorder like soldiers sent out for active duty.

Although the dysregulation of the endocannabinoid system was not found to be correlated with an increased likelihood of developing PTSD cannabis is sometimes recommended to treat PTSD. Cannabis can be relaxing for many users and minimize the feelings of anxiety for those suffering from any psychiatric disorder characterized by anxiety but it is important to note that some cannabinoids can exacerbate anxiety. Specifically, tetrahydrocannabinol (THCO, the most abundant psychoactive cannabinoid in cannabis plants, can cause some people’s anxiety to worsen, highlighting the importance of developing a standard screening technique to warn those away from THC and towards a non-psychoactive cannabinoid to manage their symptoms, such as cannabidiol (CBD).

The study is available for review or download here

Genetic-Susceptibility-to-Posttraumatic-Stress-Disorder-Analyses-of-the-Oxytocin-Receptor-Retinoic-Acid-Receptor-Related-Orphan-Receptor-A-and-Cannabinoid-Receptor-1-Genes Download

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Veterans Using Cannabis Medicinally More Likely to have PTSD than Recreational Users

October 25, 2019 Adult, Behavior change, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, Depression, Future Medicine, Impairment, Insomnia, Legislation, Opiates, Pain, PTSD, Reefer Madness, Stigma, Veterans

Title: Medicinal versus Recreational Cannabis Use among Returning Veterans

In Summary:

A recent study found significant mental and physical health differences between veterans who use cannabis that they label as “medicinal” use versus those who prefer to label their use as “recreational.” Veterans who feel that they are self-medicating with cannabis, in what they believe fits more closely with a “medical” label are five times more likely to suffer from post-traumatic stress disorder (PTSD), nearly four times more likely to suffer from Major Depressive Disorder, and are more likely to experience Insomnia, or trouble sleeping. Furthermore, a majority of veterans medicating with cannabis suffer from conditions that qualify them to receive a medical marijuana registration card. Even so, they tend to refrain from discussing their interest in access with their doctors, out of fear of losing their valuable VA benefits.

Dr. Caplan and the #MDTake:

Over the years, countless veterans have valiantly and courageously dedicated themselves to missions of support for their fellow men, women, and country. In preparation, training, service, battle, leadership, education, and so many other ways, veterans have given back to their culture in a way few others can. The understanding that they may be shunned by their culture for seeking help, related to the suffering they may have experienced while serving their country, is unconscionable. It is shameful that the government and military have not appreciated and supported the easy opportunity to give back to our veterans, and it is long overdue that the culture gives back to those who have given a piece of themselves so that others may share the liberties they have served to uphold.

group differences between medicinal and recreational cannabis users in diagnoses, cannabis-related problems, reasons for using marijuana, and other health-related and substance use outcomes

characteristics of medicinal cannabis users

Medicinal versus Recreational Cannabis Use among Returning VeteransDownload

This paper is also stored here: http://bit.ly/2MKhksv inside the CED Foundation Archive

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Video: Do-It-Yourself Cannabis Tinctures

July 17, 2019 Alcohol, Anti-inflammatory properties, Antibiotic, Antioxidant, Anxiety, Arthritis, Autism, Autoimmunity, Behavior change, Bipolar Disorder, Business of Cannabis, Cannabinoids, Cannabis, Cannabis Education, Cannabis News, Case Study, CBD, CBN, CED Clinic, CED In The News, Cognition, Colon Cancer, Cooking, Cultivation, Cultivation / Growing / Horticulture, Depression, Dermatology / Skin, Diabetes, DIY, Dosing, Dr Caplan, Edibles, Epilepsy, Extraction, Farming, Fibromyalgia, Flavonoids, Future Medicine, Gastrointestinal Effects, Hemp, History, IBS, Insomnia, Male Fertility, Memory, Mental Health, Mood, Muscle Pain, Nausea, Neuropathy, Obesity, OCD, Opiates, Oral Health, Pain, Pediatrics, Processing, Products, Prostate Cancer, Psychosis, PTSD, Schizophrenia, Seizure / Epilepsy, Sleep, Sleep Apnea, Stigma, Stress, Taste, THC, Topical, Video

One of the terrific realities of modern Cannabis is that it is possible, and often quite simple, to make effective products at home. With suitable education and access to testing facilities, the soil, nutrients, and plant growth can be supported at home, lab-tested for make-up and potency, as well as safety-checked for potential microscopic contaminants, and ultimately, individualized medicine can be created right at home!

Here is a sample instructional for just one way that cannabis tincture can be made at home. There are countless others and hopefully, many that are yet to be discovered!

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Video: Cannabinoid Intervention for PTSD: Where to Next?

July 2, 2019 Anxiety, Behavior change, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, CBD, Depression, Future Medicine, Insomnia, Memory, PTSD, Sleep, Stigma, THC, Veterans

The endocannabinoid system has long been recognized as a promising target for PTSD treatment.

Here, a 2018 literature review summarizes the risks and benefits of cannabis as a treatment option. Watch our video adaptation, and review the source literature, below:

View this review (yellow link) or download:

Cannabinoid interventions for PTSD: Where to next?Download

This paper is also stored here: http://bit.ly/2XgnrXn inside the CED Foundation Archive

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John Boehner: From Speaker of the House to Cannabis Pitchman

June 5, 2019 Cannabis News, Insomnia, PTSD, Veterans

John Boehner, the former speaker of the House, has spent his career opposing legalized marijuana. But now he sits on the board of Acreage Holdings, a marijuana investment firm whose profits hinge on Mr. Boehner’s ability to persuade Congress to legalize marijuana. The politician says that his views have “evolved,” and that he hopes cannabis will help veterans who suffer from PTSD as well as people who struggle with insomnia. #veterans #PTSD #insomnia
https://nyti.ms/2WlbpR0

Cannabidiol in the Treatment of Post-Traumatic Stress Disorder: A Case Series

June 3, 2019 Anxiety, CBD, PTSD

Cannabidiol in the Treatment of Post-Traumatic Stress Disorder: A Case Series

Preliminary findings from a study conducted on PTSD patients open a new door for cannabidiol (CBD) as a potential supplementary treatment option. CBD indirectly activates receptors linked to behavioral responses to aversive memories, a major component of the suffering involved in PTSD. The majority of participants in this review reported a decrease in the prevalence and severity of PTSD symptoms, both in the short-, and long-term. It should be taken into consideration that this study was performed with a small sample size that lacked a placebo or control group; however, this tells a familiar story to what we see in clinic. Further research will likely support cannabinoids as a legitimate treatment option for PTSD. Under the guidance of a knowledgeable Cannabis Medicine provider, PTSD patients may also consider supplementing their current treatment plan with CBD

Read more or download PDF on the CED Foundation Archive: http://bit.ly/2Kf9INN