All posts tagged: Animal

Is Cannabis Safe to Give to Animals?

A survey of veterinary student attitudes concerning whether marijuana could have therapeutic value for animals

In Summary

A recent analysis has compiled the data provided by a questionnaire sent out to veterinarians, reporting an overall belief that animals may benefit from cannabis. Very little research has been conducted concerning cannabis use in animals but some veterinarians fear that cannabis may result in toxic effects in animals. Although there is wariness due to the lack of research, many are still hopeful that cannabis products would provide similar benefits in animals as has been shown in humans. Although they may not recommend cannabis for use veterinarians are urged to educate themselves on the effects of different strains and cannabinoids so they may act according when presented with an animal who has been given cannabis products. 

While some pet owners are purposefully administering cannabis products for their animal’s accidental consumption can be incredibly frightening for some pet owners. Accidental consumption by pets highlights two important happenings that need to occur: pet owners need to ensure they are appropriately storing their cannabis product to prevent accidental consumption by pet or child, and veterinarians need to have a reliable database of knowledge concerning the possible adverse effects of cannabis on animals. Future research may save a family an accidental tragedy by appropriately information vets of their options and how to soothe their animal post-consumption. Research is needed to maintain the responsibility of pet owners and caretakers. 

The study is available for review or download here

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Benjamin Caplan, MDIs Cannabis Safe to Give to Animals?
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Cannabinoid Receptors Play Important Roles in Anti-inflammation, Anti-depression, Immune modulation, and HIV support

Cannabinoid receptor 2: Potential role in immunomodulation and neuroinflammation Review

Summary Info:

Previous research and characterization of cannabinoid receptors (CBs) have consistently demonstrated the therapeutic potential for many medical conditions. CB1, the receptor responsible for the intoxicating (and other psychoactive) effects of cannabis, has demonstrated the ability to modulate concentrations of certain other neurotransmitters, giving it the capability of acting as an antidepressant. Additionally, mice lacking CB1 receptors exhibited increased neurodegeneration, increased susceptibility for autoimmune encephalomyelitis, and inferior recovery to some traumatic nerve injuries. The CB2 receptor is generally attributed to support for modulating the immune system and calming some of the body’s natural, core inflammatory signaling systems. Activation of the receptor has been found to associate with neuroinflammatory conditions in the brain, and in appropriate circumstances, can result in the programming of cell death among some immune cells. This effect points toward a role in communication, inflammation and autoimmune diseases. Furthermore, evidence points to CB2 holding significant potential in HIV therapy. Binding partners of CB2 inhibit the HIV-1 infection and help to diminish HIV replication. Historically, these staggering findings have escaped traditional modern medical understanding. Further investigation into the therapeutic potential of cannabis, with respect to the treatment of inflammation, depression, autoimmune diseases, and HIV is at a minimum, clearly warranted for a more comprehensive understanding of effective medical therapy.

Dr Caplan and the #MDTake:

The main points here no longer seem to be investigational trends, but just pillars of Cannabis Medicine that are embarrassingly new, and poorly recognized by the modern medical establishment. While the bulk of consumers, including patients, may not engage with the science on a molecular basis, by iterative or intuitive science, individuals are diligently discovering what forms of cannabis serve their personal interests more effectively. This is, through a scientific lens, a trial-and-error adventure through products, which have various ratios of cannabinoid-receptor activation or inhibition, that ultimately achieves a similar result, which is a clinical relief for a particular ailment. Does the fact that the process does not begin with a clear understanding of the involved receptors and receptor modulators really matter? If one of the primary objectives of Medicine is to treat and/or ease suffering, and the products are built upon a bedrock of chemical safety (misuse, inappropriate, or misinformed production of products notwithstanding), it should not matter that people discover it by happy accident, or through more direct achievement.

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This paper is also stored here:      inside the CED Foundation Archive

To explore related information, click the keywords below:

Benjamin Caplan, MDCannabinoid Receptors Play Important Roles in Anti-inflammation, Anti-depression, Immune modulation, and HIV support
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