All posts tagged: cortisol

Variations in Genes Influences Cannabis’ Acute Effects on Behavior

CNR1 and FAAH variation and affective states induced by marijuana smoking

A recent study has revealed that variations within cannabinoid receptor 1 (CBR1) and fatty acid amide hydrolase (FAAH) influences cannabis’ acute effects on affect. Variations of CBR1 and FAAH are known to be associated with cannabis dependence. The current study now adds that the variations in genes also affect an individual’s behavior when ingesting cannabis. The results of this study provide useful information for understanding an individual’s motivation for marijuana use, as well as risks and associated behaviors.

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This paper is also stored here:   http://bit.ly/31Ce9Za     inside the CED Foundation Archive

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Benjamin Caplan, MDVariations in Genes Influences Cannabis’ Acute Effects on Behavior
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Recently Identified Mechanism of Chronic Stress-Induced Pain

Chronic Stress Is Associated with Pain Precipitation and Elevation in DeltaFosb Expression

Researchers have identified Delta-FosB, an osteosarcoma viral oncogene, as a useful molecular marker of sustained pain. The expression of Delta-FosB is significantly elevated by stress-induced pain, exposing its role in the adaptability of nerves. This study supports theories that Delta-FosB plays an important role in drug addiction, depression, and stress adaptation. The interaction between stress, depression, and pain is something that is not yet well-understood. But, as we learn more about cannabis-based medicine, many of the age-old questions about pain have become much clearer.

View this review (yellow link) or download:

This paper is also stored here:   http://bit.ly/31A7Y86      inside the CED Foundation Archive

To explore related information, click the keywords below:

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Benjamin Caplan, MDRecently Identified Mechanism of Chronic Stress-Induced Pain
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Cannabinoids, Terpenoids, and ALSO flavonoids

I wonder if we should be spending as much time on flavonoids as we do on terpenes (including cannabinoids)?

There is little doubt that they play a powerful effect. Just as the minor cannabinoids tend to be overlooked by much of the general & scientific cultures… flavonoids are also largely passed-over.

This study, for example, indicates that some of the components of dark chocolate reduce the body’s production of the stress hormone, cortisol (not surprising to most who have every consumed chocolate, but… did you know that those components are also found all over nature, including inside cannabis?!)

I’ll start adding flavonoids to the list of info to start sharing!

http://bit.ly/2W6C0w8

Benjamin Caplan, MDCannabinoids, Terpenoids, and ALSO flavonoids
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