All posts tagged: pain

Recently Identified Mechanism of Chronic Stress-Induced Pain

June 22, 2019 Addiction, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Cognition, Cortisol, Depression, Future Medicine, History, Mental Health, Pain, Science, Stress, THC

Chronic Stress Is Associated with Pain Precipitation and Elevation in DeltaFosb Expression

Researchers have identified Delta-FosB, an osteosarcoma viral oncogene, as a useful molecular marker of sustained pain. The expression of Delta-FosB is significantly elevated by stress-induced pain, exposing its role in the adaptability of nerves. This study supports theories that Delta-FosB plays an important role in drug addiction, depression, and stress adaptation. The interaction between stress, depression, and pain is something that is not yet well-understood. But, as we learn more about cannabis-based medicine, many of the age-old questions about pain have become much clearer.

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Chronic Stress Is Associated with Pain Precipitation and Elevation in DeltaFosb Expression Download

This paper is also stored here: http://bit.ly/31A7Y86 inside the CED Foundation Archive

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Safety and Efficacy of Medical Cannabis in Fibromyalgia

June 21, 2019 Anti-inflammatory properties, Arthritis, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CED In The News, Fibromyalgia, Future Medicine, Muscle Pain, Neuropathy, Pain, Science, THC

In a study of 367 patients, researchers investigated the safety and effectiveness of cannabis consumption to treat fibromyalgia symptoms. After treatment with cannabis, pain intensity (scale 0–10) reports reduced from a median of 9.0 to a median of 5.0. Interestingly, patients who had previously used cannabis were more likely to have treatment success, whereas patients who shared concerns about cannabis treatment were more likely to have treatment failure. A patient’s mindset can directly affect their treatment outcome.

At CED Clinic, we use the power of education to help patients feel comfortable and confident with their treatment plan.

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Safety and Efficacy of Medical Cannabis in Fibromyalgia Download

This paper is also stored here: http://bit.ly/2WWLyz6 inside the CED Foundation Archive

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Honey and Garlic Help Heal Burn Wounds

June 18, 2019 Animal Model, Anti-inflammatory properties, Dermatology / Skin, Extraction, Flavonoids, Future Medicine, Neuropathy, Non-Cannabis Plant, Pain, Placebo-Controlled, Processing, Products, Science, Terpenes

Euphorbia honey and garlic- Biological activity and burn wound recovery

A recent study has shown that a combination of euphorbia honey and garlic can help heal burn wounds. Euphorbia honey and garlic have antioxidant, microbial, and healing properties that have now been confirmed to be effective when treating wounds resulting from exposure to extreme heat. Combining natural ingredients has been common in traditional medicine for years, but now western medicine is beginning to look at more natural compounds to aid in recovery and treatment methods.

This paper is also stored here: http://bit.ly/2Fbqk5F inside the CED Foundation Archive

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Euphorbia honey and garlic- Biological activity and burn wound recovery
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Evidence for Therapeutic Benefits of Cannabidiol, Including Treatment of Ischemic Strokes

June 17, 2019 Adolescents, Adverse Effects, Alzheimer's Disease, Anti-inflammatory properties, Autoimmunity, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Cognition, Concussion, Elderly, Future Medicine, Heavy Use, Insomnia, Memory, Mental Health, Neuropathy, Pain, Stigma, THC

Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke

Cannabidiol (CBD) has a unique therapeutic profile as it has a cannabinoid receptor-independent mechanism, limited side-effects, and patients do not seem to develop an insurmountable tolerance. Research currently focussed on the therapeutic benefits of CBD has demonstrated long-lasting neuroprotective properties against global and focal ischemic injury, such as ischemic stroke. This piece points to CBD as a major component of cannabis-based medicine as a non-psychoactive component. Further research is needed to evaluate the full clinical capabilities of CBD, including its neuroprotective effect.

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Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke Download

The US patent on Cannabinoids as Antioxidants and Neuroprotectants, from 1999: https://patents.google.com/patent/US6630507B1/en

This paper is also stored here: http://bit.ly/2L0PBn3 inside the CED Foundation Archive

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Researchers Look to CBD and THC for the Treatment of Chronic Pain

June 17, 2019 Adverse Effects, Arthritis, Behavior change, Cannabinoids, Cannabis, Cannabis Science, CB1, CB2, CBD, Future Medicine, Pain, Products, Science

Efficacy and safety of cannabidiol followed by an open-label add-on of tetrahydrocannabinol for the treatment of chronic pain in patients with rheumatoid arthritis or ankylosing spondylitis: protocol for a multicentre, randomized, placebo-controlled study

Current researchers have proposed a study protocol that would expose any possible benefits of cannabidiol (CBD) and tetrahydrocannabinol (THC) for the treatment of chronic pain in patients suffering from rheumatoid arthritis (RA) and ankylosing spondylitis (AS). This new study hopes to identify how medical cannabis affects pain and cognitive function in RA and AS and provide evidence that cannabis-based pain medication is an alternative to opioids with fewer risks.

This paper is also stored here: http://bit.ly/2Fb08s5 inside the CED Foundation Archive

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The Education of Dispensary Staff is Varied and Lacks Regulation

June 17, 2019 Adolescents, Anti-inflammatory properties, Anxiety, Arthritis, Behavior change, Cannabinoids, Cannabis, Cannabis Education, Cannabis News, CBD, Citizen Science, Depression, Dispensaries, Elderly, Future Medicine, History, Legislation, Mental Health, Mood, Neuropathy, Obesity, Pain, Pediatrics, Politics, Regulation, Science, Social Equity, Social Justice, Stigma, THC, Withdrawal, Women in Cannabis

Training and Practices of Cannabis Dispensary Staff

How much medical training does your local budtender possess? An online survey sent to medical marijuana dispensary staff reported only 55% of staffers had any formal training for their position, with 20% reporting some background in medical/scientific training. The analysis reported that many among the dispensary staff are recommending cannabis choices that are consistent with current evidence, but some are recommending strains that are either ineffective or exacerbate a patient’s condition. The findings of this study stress the importance of consistent and well-regulated training of dispensary staff.

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This paper is also stored here: http://bit.ly/2FfJNSC inside the CED Foundation Archive

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Video: Cannabis For Symptoms of chronic pain, seizures, and inflammation

June 10, 2019 Adverse Effects, Anti-inflammatory properties, Anxiety, Arthritis, Cannabinoids, Cannabis, Cannabis Education, Cannabis News, Cannabis Science, CB1, CB2, CBD, Citizen Science, Depression, Dronabinol, Elderly, Flavonoids, Future Medicine, Heavy Use, History, IBS, Insomnia, Neuropathy, Occasional Use, Opiates, Overdose, Pain, Psychosis, Schizophrenia, Science, Sleep, Stigma, THC, Withdrawal

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Preferences for Medical Marijuana over Prescription Medications Among Persons Living with Chronic Conditions- Alternative, Complementary, and Tapering Uses Download

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Some, But Not Enough Data on Cannabis for Chronic Pain

June 10, 2019 Arthritis, Cannabinoids, Cannabis, Cannabis Education, Cannabis Science, CB1, CB2, CBD, Future Medicine, Muscle Pain, Neuropathy, Pain, Science, THC

Overlaps in pharmacology for the treatment of chronic pain and mental health disorders

Select small trials have demonstrated cannabis to be more effective than other analgesics to treat chronic pain associated with certain conditions. However, the existing research lacks large-scale, controlled experiments relating medical cannabis use to pain management. Additionally, negative effects are documented with respect to cannabis use among adolescents and those suffering from compromised mental health. There is a need for further research on the topic.

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Cannabis use & older adults

May 31, 2019 Cannabis News, Elderly

Cannabis use by older adults is increasingly common: rates of use by age group are increasing most rapidly among adults older than 65. Adults use #cannabis for #depression, #anxiety, #pain and more. Learn more at http://bit.ly/2WyxA5I