Adverse Effects

Adolescent Executive Dysfunction in Daily Life: Relationships to Risks, Brain Structure and Substance Use

Researchers assessed 817 youth (aged 12 to 21) who previously participated in the National Consortium on Alcohol and Neurodevelopment in Adolescence study. They found that 123 subjects (15.2%) had used cannabis in the past year, and that cannabis use impaired inhibitory control, emotional control, and task planning.

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This paper is also stored here:    http://bit.ly/2L0aMWa     inside the CED Foundation Archive

Benjamin Caplan, MDAdolescent Executive Dysfunction in Daily Life: Relationships to Risks, Brain Structure and Substance Use
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How to prevent inappropriate teen use?

Especially in Colorado and Washington, people are taking note of teens’ use and access to potent marijuana, and many are concerned that there are not enough measures in place to prevent this. Newly legalized states should look into this before it becomes a national issue. https://wapo.st/2Fgmto9

Benjamin Caplan, MDHow to prevent inappropriate teen use?
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Evidence for Therapeutic Benefits of Cannabidiol, Including Treatment of Ischemic Strokes

Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke

Cannabidiol (CBD) has a unique therapeutic profile as it has a cannabinoid receptor-independent mechanism, limited side-effects, and patients do not seem to develop an insurmountable tolerance. Research currently focussed on the therapeutic benefits of CBD has demonstrated long-lasting neuroprotective properties against global and focal ischemic injury, such as ischemic stroke. This piece points to CBD as a major component of cannabis-based medicine as a non-psychoactive component. Further research is needed to evaluate the full clinical capabilities of CBD, including its neuroprotective effect.

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The US patent on Cannabinoids as Antioxidants and Neuroprotectants, from 1999: https://patents.google.com/patent/US6630507B1/en

This paper is also stored here:    http://bit.ly/2L0PBn3     inside the CED Foundation Archive

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Benjamin Caplan, MDEvidence for Therapeutic Benefits of Cannabidiol, Including Treatment of Ischemic Strokes
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Researchers Look to CBD and THC for the Treatment of Chronic Pain

Efficacy and safety of cannabidiol followed by an open-label add-on of tetrahydrocannabinol for the treatment of chronic pain in patients with rheumatoid arthritis or ankylosing spondylitis: protocol for a multicentre, randomized, placebo-controlled study

Current researchers have proposed a study protocol that would expose any possible benefits of cannabidiol (CBD) and tetrahydrocannabinol (THC) for the treatment of chronic pain in patients suffering from rheumatoid arthritis (RA) and ankylosing spondylitis (AS). This new study hopes to identify how medical cannabis affects pain and cognitive function in RA and AS and provide evidence that cannabis-based pain medication is an alternative to opioids with fewer risks.

This paper is also stored here:    http://bit.ly/2Fb08s5     inside the CED Foundation Archive

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Benjamin Caplan, MDResearchers Look to CBD and THC for the Treatment of Chronic Pain
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A Call for Physicians to Embrace Medicinal Cannabis as a Virtuoso of Prudence

The Prescription of Medicinal Cannabis and the Virtue of Prudence: Without Phobia(S) Nor Philia(S)

A passionate physician shared his opinion on prescribing patients medicinal cannabis, promoting its use in accordance with the virtue of prudence. The piece implores physicians to identify the medicinal benefits of cannabis and embrace its side effects without fear. Medicinal cannabis has its place among prescriptions with “respect for leges artis” as long as the decision to recommend cannabis is the result of an ethical-clinically based decision.  

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This paper is also stored here:     http://bit.ly/2Ff3mLc    inside the CED Foundation Archive

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Benjamin Caplan, MDA Call for Physicians to Embrace Medicinal Cannabis as a Virtuoso of Prudence
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Organ Donors can Safely Consume Cannabis

Effects of Drug Abuse, Smoking and Alcohol on Donor Hearts and Lungs

A review article that discusses how drug use can affect donor organs has revealed that receiving organs, such as a heart or lungs, from a donor who has used cannabis does not add risk to the procedure. A careful assessment of any donor organ should still be conducted, but having a history of cannabis use does not prevent someone from safely donating.

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This paper is also stored here:   http://bit.ly/2KPxsIx      inside the CED Foundation Archive

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Benjamin Caplan, MDOrgan Donors can Safely Consume Cannabis
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Cognitive Function in Aging Cocaine Smokers is Marginally Lower than Controls

Cognitive function in aging cocaine smokers

A recently published study looking to expose the functional status of older drug users has found that most of their cognitive abilities are equal to their peers who have never smoked cocaine, except for a marginally lower verbal comprehension. Similar studies should continue in order to determine how chronic drug users will affect or challenge public health systems in the future.

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This paper is also stored here:    http://bit.ly/2FbOUmZ      inside the CED Foundation Archive

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Benjamin Caplan, MDCognitive Function in Aging Cocaine Smokers is Marginally Lower than Controls
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High-potency cannabis and incident psychosis: correcting the causal assumption

Scientists offer a strong counter-position to the belief that cannabis causes psychosis, pointing out the difference between correlation and causation. They argue that smoke exposure from any source (including cigarettes) could explain the reported link between cannabis and psychosis. 

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This paper is also stored here:    http://bit.ly/2WHtDr8     inside the CED Foundation Archive

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Benjamin Caplan, MDHigh-potency cannabis and incident psychosis: correcting the causal assumption
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Multiple Health Risk Behaviors in Young Adult Smokers: Stages of Change and Stability over Time

Study finds that most young adult smokers engage in multiple other health risk behaviors. When placed in an intervention, participants were most ready to change their stress management and least ready to change their cannabis use.

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This paper is also stored here:  http://bit.ly/31mTqIM       inside the CED Foundation Archive

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Benjamin Caplan, MDMultiple Health Risk Behaviors in Young Adult Smokers: Stages of Change and Stability over Time
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A 2018 study finds that cannabis can alleviate symptoms of medications used for chronic pain as well as serve as an alternative treatment for seizures, pain, and inflammation.

Benjamin Caplan, MDA 2018 study finds that cannabis can alleviate symptoms of medications used for chronic pain as well as serve as an alternative treatment for seizures, pain, and inflammation.
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