In a study of 661, 617 pregnant women, researchers found that cannabis use was significantly associated with an increased risk of preterm birth. But these findings may be limited due to other risk factors like tobacco, alcohol, and opioid use.
Especially in Colorado and Washington, people are taking note of teens’ use and access to potent marijuana, and many are concerned that there are not enough measures in place to prevent this. Newly legalized states should look into this before it becomes a national issue. https://wapo.st/2Fgmto9
Benjamin Caplan, MDHow to prevent inappropriate teen use?
Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke
Cannabidiol (CBD) has a unique therapeutic profile as it has a cannabinoid receptor-independent mechanism, limited side-effects, and patients do not seem to develop an insurmountable tolerance. Research currently focussed on the therapeutic benefits of CBD has demonstrated long-lasting neuroprotective properties against global and focal ischemic injury, such as ischemic stroke. This piece points to CBD as a major component of cannabis-based medicine as a non-psychoactive component. Further research is needed to evaluate the full clinical capabilities of CBD, including its neuroprotective effect.
Effects of Drug Abuse, Smoking and Alcohol on Donor Hearts and Lungs
A review article that discusses how drug use can affect donor organs has revealed that receiving organs, such as a heart or lungs, from a donor who has used cannabis does not add risk to the procedure. A careful assessment of any donor organ should still be conducted, but having a history of cannabis use does not prevent someone from safely donating.
A recently published study looking to expose the functional status of older drug users has found that most of their cognitive abilities are equal to their peers who have never smoked cocaine, except for a marginally lower verbal comprehension. Similar studies should continue in order to determine how chronic drug users will affect or challenge public health systems in the future.
Study finds that most young adult smokers engage in multiple other health risk behaviors. When placed in an intervention, participants were most ready to change their stress management and least ready to change their cannabis use.
Guanfacine decreases symptoms of cannabis withdrawal in daily cannabis smokers
A study performed on daily cannabis users with cannabis use disorder (CUD) found evidence for Guanfacine to reduce the irritability and disturbances to sleep, characteristic of cannabis withdrawal. It is potentially a viable, improved alternative to Lofexidine, another treatment for CUD which happens to result in some adverse effects, including drowsiness, dizziness, and altered food intake. However, beyond these effects, while Lofexidine reduced cannabis self-administration following abstinence, Guanfacine did not in this study. Regardless, further research on the therapeutic effects of Guanfacine may be worthwhile and could help reduce cannabis cravings following withdrawal.
Effect of Smoked Cannabis on Vigilance and Accident Risk Using Simulated Driving in Occasional and Chronic Users and the Pharmacokinetic-Pharmacodynamic Relationship
In a study comparing the short-term effects of cannabis consumption on occasional and chronic cannabis users, occasional users were found to have slower reaction times, experience effects sooner, and have cannabis persist in their bloodstream longer than among chronic cannabis users. Both occasional and chronic users experienced impaired reaction times that affected their performance in a driving simulation. Both chronic and occasional marijuana users should be cognizant of the amount of time in which they are impaired following cannabis consumption and abstain from driving.
DSM-5 cannabis withdrawal syndrome: Demographic and clinical correlates in U.S. adults
Cannabis withdrawal syndrome affects approximately 12.1% of heavy cannabis users and is characterized by symptoms such as nervousness/anxiety, hostility, sleep difficulty, and depressed mood. It has increased prevalence among those suffering from mood disorders, anxiety disorders, and personality disorders. This new data should emphasize the need for physicians to exercise caution when recommending cannabis to individuals who may end up consuming cannabis heavily, and who also suffering from mood, anxiety, or personality disorders