Scientists offer a strong counter-position to the belief that cannabis causes psychosis, pointing out the difference between correlation and causation. They argue that smoke exposure from any source (including cigarettes) could explain the reported link between cannabis and psychosis.
A study in March found that daily use of high-potency cannabis is “strongly linked to the risk of developing psychosis.” But on June 1st, six scientists published a study in The Lancet, a British medical journal, that disputed this claim. The authors of the study note that correlation doesn’t equal causation. In other words, people with schizophrenia may be more likely to use cannabis, but there’s no evidence to suggest that it works the other way around. #psychosis #schizophrenia The news: http://bit.ly/2WeuM9E The articles & academic commentary: http://bit.ly/2Wf04wT
Benjamin Caplan, MDDoes cannabis cause psychosis? Evidence is lacking, scientists say
CBD Shows Promise for Schizophrenia, Alzheimer’s, and Brain Injury Patients
A meta-analysis of previous studies investigating cannabidiol’s (CBD) potential to improve cognitive function among schizophrenia and brain injury patients offers hope to doctors and patients. In experiments on both human patients and rat models of schizophrenia, Alzheimer’s Disease, hypoxic-ischemic brain injury, hepatic encephalopathy, sepsis, pneumococcal meningitis, and cerebral malaria, the administration of CBD reduced neuroinflammation and resulting deficits in spatial learning and memory, recognition memory, and associative learning. Read more or download PDF on the CED Foundation Archive: http://bit.ly/2W1PpW8
In this same review, further investigating the effect of the non-psychoactive cannabidiol (CBD) on cognitive function suggests CBD counteracts the cognitive deficiencies induced by the psychoactive component of cannabis, delta-9-tetrahydrocannabinol (THC). Studies performed on humans and rat models demonstrated that CBD can improve episodic and recognition memory, verbal and visual learning and memory, and working memory, all skills which are usually impaired by THC content. For patients looking to reduce the aforementioned undesirable effects of cannabis, strains or products with high CBD and low THC content may be a viable solution.
Benjamin Caplan, MDA systematic review of the effect of cannabidiol on cognitive function: Relevance to schizophrenia
Research on schizophrenia-affected rat models shows potential for #CBD to minimize many #schizophrenia symptoms
Cannabidiol (CBD) may have potential as a schizophrenia therapeutic agent. Individuals with schizophrenia exhibit decreased activity in choline acetyltransferase (ChAT) activity, an enzyme associated with cognitive functioning. In rat models mimicking schizophrenia, affected rats treated with CBD exhibited normal ChAt activity, while their untreated counterparts exhibited reduced activity.