All posts tagged: Anti-Inflammatory

Efficacy of Cannabinoids in a Pre-Clinical Drug-Screening Platform for Alzheimer’s Disease

Researchers find 9 cannabinoids that might protect the brain against toxicities associated with aging. These non-intoxicating cannabinoids are potential drug candidates for Alzheimer’s Disease, and they might also be options for other neurodegenerative diseases, too

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Benjamin Caplan, MDEfficacy of Cannabinoids in a Pre-Clinical Drug-Screening Platform for Alzheimer’s Disease
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Honey and Garlic Help Heal Burn Wounds

Euphorbia honey and garlic- Biological activity and burn wound recovery

A recent study has shown that a combination of euphorbia honey and garlic can help heal burn wounds. Euphorbia honey and garlic have antioxidant, microbial, and healing properties that have now been confirmed to be effective when treating wounds resulting from exposure to extreme heat. Combining natural ingredients has been common in traditional medicine for years, but now western medicine is beginning to look at more natural compounds to aid in recovery and treatment methods.

This paper is also stored here:  http://bit.ly/2Fbqk5F   inside the CED Foundation Archive

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Benjamin Caplan, MDHoney and Garlic Help Heal Burn Wounds
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Evidence for Therapeutic Benefits of Cannabidiol, Including Treatment of Ischemic Strokes

Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke

Cannabidiol (CBD) has a unique therapeutic profile as it has a cannabinoid receptor-independent mechanism, limited side-effects, and patients do not seem to develop an insurmountable tolerance. Research currently focussed on the therapeutic benefits of CBD has demonstrated long-lasting neuroprotective properties against global and focal ischemic injury, such as ischemic stroke. This piece points to CBD as a major component of cannabis-based medicine as a non-psychoactive component. Further research is needed to evaluate the full clinical capabilities of CBD, including its neuroprotective effect.

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The US patent on Cannabinoids as Antioxidants and Neuroprotectants, from 1999: https://patents.google.com/patent/US6630507B1/en

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Benjamin Caplan, MDEvidence for Therapeutic Benefits of Cannabidiol, Including Treatment of Ischemic Strokes
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Flavonoids Found in Buckwheat Hulls Have Antioxidant Properties

Flavonoids in common and Tartary Buckwheat hull extracts and antioxidant activity of the extracts against lipids in mayonnaise

A recent study has revealed that the various flavonoids in buckwheat hulls are a reliable source for antioxidant material. When a buckwheat hull extract was made and exposed to mayonnaise, the shelf-life of the mayonnaise was extended, likely related to the antioxidant properties. This study was able to determine the effectiveness of extracts from the common and Tartary Buckwheat hulls, as well as provide an efficient extraction method.

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Benjamin Caplan, MDFlavonoids Found in Buckwheat Hulls Have Antioxidant Properties
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The Education of Dispensary Staff is Varied and Lacks Regulation

Training and Practices of Cannabis Dispensary Staff

How much medical training does your local budtender possess? An online survey sent to medical marijuana dispensary staff reported only 55% of staffers had any formal training for their position, with 20% reporting some background in medical/scientific training. The analysis reported that many among the dispensary staff are recommending cannabis choices that are consistent with current evidence, but some are recommending strains that are either ineffective or exacerbate a patient’s condition. The findings of this study stress the importance of consistent and well-regulated training of dispensary staff.

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Benjamin Caplan, MDThe Education of Dispensary Staff is Varied and Lacks Regulation
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Compounds in Citrus Peels Functioning as Preventive Agents for Prostate Cancer

Effect of citrus peel extracts on the cellular quiescence of prostate cancer cells

A recent study has revealed that citrus peel extracts (CPE) have the potential to prevent prostate cancer from recurring in post-therapy cancer patients. A component of CPE, flavonoids, have previously been found to have anticancer effects, but appear to lack the correct structure to prevent tumors in patients with prostate cancer. This specific study found that the citric acid present in CPE was the contributing factor to its anticancer effects but mentioned that flavonoids should continue to be researched for chemopreventive benefits.

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Benjamin Caplan, MDCompounds in Citrus Peels Functioning as Preventive Agents for Prostate Cancer
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Flavonoids May Provide Therapeutic Benefits for Type 2 Diabetes

A recent study has found that flavonoids isolated from Psoralea corylifolia are able to inhibit part of the insulin pathway.

Seeds of the P. corylifolia plant have been used in eastern medicine, primary in China, for years, and is now being further researched as flavonoids continue to intrigue researchers with their possible therapeutic benefits. The inhibitory activity found in this study provides evidence that flavonoids should be pursued as a potential treatment for Type-2 Diabetes.

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Benjamin Caplan, MDFlavonoids May Provide Therapeutic Benefits for Type 2 Diabetes
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New Extraction Methods for “Polyphenols” Benefits Future Research

Citrus peels waste as a source of value-added compounds- extraction and quantification of bioactive polyphenols

A recent study has exposed a more efficient, sustainable, and economically viable extraction method for polyphenols (specific active chemical compounds) from citrus peels. One such polyphenol is Naringin, a flavonoid present in lemon peels, which has been hypothesized to have anti-inflammatory and antioxidant effects, as well as, potentially, to help treat obesity. This new extraction method will allow researchers to discover more definite therapeutic effects of polyphenols in citrus peels.

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Benjamin Caplan, MDNew Extraction Methods for “Polyphenols” Benefits Future Research
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Influence of the CB1 cannabinoid receptors & antidepressant effects

Study finds that, for patients already taking antidepressants, activating and/or prohibiting the CB1 receptor in the brain might make those antidepressants more effective.

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Benjamin Caplan, MDInfluence of the CB1 cannabinoid receptors & antidepressant effects
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A 2018 study finds that cannabis can alleviate symptoms of medications used for chronic pain as well as serve as an alternative treatment for seizures, pain, and inflammation.

Benjamin Caplan, MDA 2018 study finds that cannabis can alleviate symptoms of medications used for chronic pain as well as serve as an alternative treatment for seizures, pain, and inflammation.
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