All posts tagged: Anti-Inflammatory

Flavonoids May Provide Therapeutic Benefits for Type 2 Diabetes

A recent study has found that flavonoids isolated from Psoralea corylifolia are able to inhibit part of the insulin pathway.

Seeds of the P. corylifolia plant have been used in eastern medicine, primary in China, for years, and is now being further researched as flavonoids continue to intrigue researchers with their possible therapeutic benefits. The inhibitory activity found in this study provides evidence that flavonoids should be pursued as a potential treatment for Type-2 Diabetes.

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Benjamin Caplan, MDFlavonoids May Provide Therapeutic Benefits for Type 2 Diabetes
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New Extraction Methods for “Polyphenols” Benefits Future Research

Citrus peels waste as a source of value-added compounds- extraction and quantification of bioactive polyphenols

A recent study has exposed a more efficient, sustainable, and economically viable extraction method for polyphenols (specific active chemical compounds) from citrus peels. One such polyphenol is Naringin, a flavonoid present in lemon peels, which has been hypothesized to have anti-inflammatory and antioxidant effects, as well as, potentially, to help treat obesity. This new extraction method will allow researchers to discover more definite therapeutic effects of polyphenols in citrus peels.

View this review (yellow link) or download:

This paper is also stored here:    http://bit.ly/2F7XrXY    inside the CED Foundation Archive

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Benjamin Caplan, MDNew Extraction Methods for “Polyphenols” Benefits Future Research
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Influence of the CB1 cannabinoid receptors & antidepressant effects

Study finds that, for patients already taking antidepressants, activating and/or prohibiting the CB1 receptor in the brain might make those antidepressants more effective.

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Benjamin Caplan, MDInfluence of the CB1 cannabinoid receptors & antidepressant effects
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Video: Cannabis For Symptoms of chronic pain, seizures, and inflammation

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Benjamin Caplan, MDVideo: Cannabis For Symptoms of chronic pain, seizures, and inflammation
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Synthetic Cannabinoids Provide Evidence for Targeting Cannabinoid Receptors in the Treatment of Autoimmune Diseases

Pharmaceutical Cannabis Derivatives Help Discover their Receptors and Functions for Autoimmune Illnesses

A recent study conducted by Michigan State University exposed the potential for cannabinoid receptor 2 (CB2) to target the treatment of inflammatory conditions. Elevated levels of plasmacytoid dendritic cells (pCD, a type of cell in the immune system) contribute to chronic inflammation in autoimmune diseases, such as Rheumatoid Arthritis. Researchers found that synthetic CB2 agonists reported comparable benefits to THC, but minimized the cerebral effects as the psychotropic activity is mediated by cannabinoid receptor 1 (CB1). This evidence demonstrates the potential benefits of CB2-targeted treatment for inflammatory conditions. Unfortunately, there are serious concerns about the misuse of some synthetic cannabinoids, so there is still a missing bridge, in products and public education, between these research products and potential therapeutic pharmaceuticals, down the road.

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Benjamin Caplan, MDSynthetic Cannabinoids Provide Evidence for Targeting Cannabinoid Receptors in the Treatment of Autoimmune Diseases
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A selective CB2 agonist protects against the inflammatory response and joint destruction in collagen-induced arthritis mice

In a study of 40 mice, scientists find that the CB2-selective agonist significantly reduced the severity of arthritis and markedly reduced bone erosion. These data clearly indicate that the CB2-selective agonist may be considered a novel treatment for rheumatoid arthritis.

Benjamin Caplan, MDA selective CB2 agonist protects against the inflammatory response and joint destruction in collagen-induced arthritis mice
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Four Chinese Fern Species Possess Anti-inflammatory Properties

Evaluation of the Anti-inflammatory and Antioxidative Potential of Four Fern Species from China Intended for Use as Food Supplements:

Four fern species, Matteuccia struthiopteris, Osmunda japonica, Matteuccia orientalis, and Pteridium aquilinum are food sources, commercially available on Chinese markets. In a recent study investigating the medicinal properties of select plants, these four ferns were also found to have anti-inflammatory and anti-oxidative properties. All four ferns inhibit expression of IL1-β, a pro-inflammatory gene. These results support an investigation of other common wild edible plants with respect to their potential for medicinal use.

Cannabis may just open up a refreshing look at countless other plants available to those who appreciate the opportunity.

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Benjamin Caplan, MDFour Chinese Fern Species Possess Anti-inflammatory Properties
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