A recent study has found that flavonoids isolated from Psoralea corylifolia are able to inhibit part of the insulin pathway.
Seeds of the P. corylifolia plant have been used in eastern medicine, primary in China, for years, and is now being further researched as flavonoids continue to intrigue researchers with their possible therapeutic benefits. The inhibitory activity found in this study provides evidence that flavonoids should be pursued as a potential treatment for Type-2 Diabetes.
Citrus peels waste as a source of value-added compounds- extraction and quantification of bioactive polyphenols
A recent study has exposed a more efficient, sustainable, and economically viable extraction method for polyphenols (specific active chemical compounds) from citrus peels. One such polyphenol is Naringin, a flavonoid present in lemon peels, which has been hypothesized to have anti-inflammatory and antioxidant effects, as well as, potentially, to help treat obesity. This new extraction method will allow researchers to discover more definite therapeutic effects of polyphenols in citrus peels.
Cannabinoid receptors, located throughout the body, are involved in a variety of physiological processes (including appetite, mood, etc.). A 2019 study shows that blocking CB1Rs (cannabinoid receptors that conserve energy) is an effective way to manage metabolic disorders, such as obesity and Type-2 Diabetes.
Because of the associated anti-inflammatory action, modulation of CB1R & CB2R is helpful to treat autoimmune diseases, including Multiple Sclerosis, Type-1 Diabetes Mellitus, and Rheumatoid Arthritis The full list is truly very much longer, as every illness necessarily involves the immune system and cellular communication.
The following review, written by Elaine D. Gonc ̧alves