All posts tagged: Products

Medicinal Value of Citrus Peels

Citrus peels waste as a source of value-added compounds: extraction and quantification of bioactive polyphenols

Previous analysis of citrus peels has demonstrated high content of biologically active polyphenols, with significant quantities of flavonoids and phenolic acids present. Both these compounds have been associated with antioxidant, anti-inflammatory, antiproliferative, anti-allergic, antiviral, anticarcinogenic, neuroprotective, and antimicrobial properties.

A recent paper points out that citrus peel waste alone makes up nearly 50% of wet fruit mass discarded as waste and proposes extraction of polyphenols to minimize waste. The bioactive substances in peels can be used in dietary supplements, cosmetics, food products, and pharmaceutical products.

Citrus peels contain significant polyphenols, compounds which have health benefits ranging from antioxidant to anticancer. Polyphenols are also found in large quantities in cannabis, undoubtedly contributing to it many of its well-known health benefits. 

Image result for citrus peel eating

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This paper is also stored here:    http://bit.ly/2F8bPja     inside the CED Foundation Archive

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Benjamin Caplan, MDMedicinal Value of Citrus Peels
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In Vivo Availability of Cannabinoid 1 Receptor Levels in Patients With First-Episode Psychosis

A 2019 study found that patients with early-stage psychotic disorders had lower levels of CB1-R (Cannabinoid Receptor – 1) compared to healthy individuals. These findings suggest that targeting CB1R with cannabis-based products could potentially treat psychotic disorders. Interestingly, reductions in CB1R levels were associated with greater symptom severity and poorer cognitive functioning but only in male patients. More research is needed into the intersections of gender and psychotic disorders.

View this review (yellow link) or download:

This paper is also stored here:   http://bit.ly/2XEkpfV      inside the CED Foundation Archive

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Benjamin Caplan, MDIn Vivo Availability of Cannabinoid 1 Receptor Levels in Patients With First-Episode Psychosis
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Topical Cannabis to help heal chronic wounds

Another thoughtful piece by Abbie Rosner at Forbes, reviewing the healing of chronic wounds with topical cannabis treatments.

https://www.forbes.com/sites/abbierosner/2019/07/09/cannabis-based-medicine-a-breakthrough-for-healing-intractable-chronic-wounds/#7b1362bf9387

Benjamin Caplan, MDTopical Cannabis to help heal chronic wounds
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Video: Cannabinoid Delivery Systems for Pain and Inflammation Treatment

A 2018 literature review summarizes the various ways patients can consume cannabis (orally, topically, etc.) and the pain reductions associated with each method. The review focuses on the treatment of multiple sclerosis, cancer, anorexia, arthritis, and other painful disorders.

View this review (yellow link) or download:

This paper is also stored here:    http://bit.ly/2TSZ2Wr     inside the CED Foundation Archive

Benjamin Caplan, MDVideo: Cannabinoid Delivery Systems for Pain and Inflammation Treatment
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Patients are Unclear on Cannabis Dosing

Dr. Ernest found that 82% of her epileptic patients found cannabis treatment helpful, but she also found that many of them were unaware of the doses they were taking or the levels of THC and CBD. Doctors and patients alike need to learn about dosing to maximize their health benefits http://bit.ly/2J29kkB

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Benjamin Caplan, MDPatients are Unclear on Cannabis Dosing
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Israel and the global cannabis market

Some believe that it is difficult to compete with industry giants, such as Tilray and Cronos. But, Israel’s long history of cannabis research and its innovative companies, leading tech and strong agricultural climate make it a likely region to attract many in the global cannabis market. http://bit.ly/2IPXbz8

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Benjamin Caplan, MDIsrael and the global cannabis market
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The Cannabinoid System is a Promising Source of Targets for Treating Pain

A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain ECS

The cannabinoid system provides momentum to develop cannabinoid-based medications to treat inflammatory and neuropathic pain as researchers continue to find promising therapeutic targets. These new targets may lead to the formation of novel pain-relief medications that may serve well to alleviate pain for those suffering from cancer, multiple sclerosis, and fibromyalgia. Cannabis-based pain medicine is also being researched for opioid-sparing effects and effectiveness in reducing the necessary dose of opioids.

View this review (yellow link) or download:

This paper is also stored here:  http://bit.ly/2FfLorA        inside the CED Foundation Archive

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Benjamin Caplan, MDThe Cannabinoid System is a Promising Source of Targets for Treating Pain
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Neem Oil vs Cannabinoid Hyperemesis Syndrome

Some people are concerned that Cannabinoid Hyperemesis Syndrome (CHS,) a rare condition involving cyclical vomiting, may be caused by neem oil or pesticides. However, symptoms are more consistent with an overload of CB1 receptors, circumstances that occur primarily with habitual, large-volume consumers. Here, an interesting review of the ongoing public conversation: http://bit.ly/2LepwAV

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Benjamin Caplan, MDNeem Oil vs Cannabinoid Hyperemesis Syndrome
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Cost-effectiveness of treating pediatric drug-resistant epilepsy

Cannabis-based treatments may reduce seizures among children with drug-resistant epilepsy, but are these treatments cost-effective? 

Economic evaluations of cannabis treatments are needed, and they should address issues including weight-gain over time, switching or discontinuation of treatments, the effectiveness of interventions, and long-term success, beyond the duration of available clinical studies.

This paper is also stored here:     http://bit.ly/2INWAOJ    inside the CED Foundation Archive

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Benjamin Caplan, MDCost-effectiveness of treating pediatric drug-resistant epilepsy
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US House of Representatives votes to support state legal cannabis

Kudos to Kyle Jaeger for a helpful summary of last week’s US House’s vote on an amendment to block the Department of Justice from interfering in states’ legal cannabis programs. His work outlines which representatives stand where, with regard to #cannabis. Interesting to see, and how times change! http://bit.ly/2LgKO0P

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Benjamin Caplan, MDUS House of Representatives votes to support state legal cannabis
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